Pharmacology exams rarely ask what a drug is called. They ask what you would check before giving it, what you would do if a patient’s pulse dropped, and what you would tell someone before they go home. Many students know the drug facts and still lose points because the question is about nursing judgment, not recall.
This test bank was built to give you practice with that judgment. It follows the chapter order of Clayton’s Basic Pharmacology for Nurses, 20th Edition, by Michelle Willihnganz and Samuel L. Gurevitz, so each study session matches what your class is covering.
If you are in your first pharmacology course, getting ready for clinical days with medication passes, or reviewing for the NCLEX-RN, this resource gives you steady practice with safe, clear decision-making.
Topics Covered
The question sets follow the textbook and include:
- How drugs enter, move through, and leave the body
- Safe medication administration, including the rights of medication use
- Dosage calculations and measuring liquid and injectable doses
- Drug interactions, side effects, and allergic reactions
- Heart, blood pressure, and cholesterol medicines
- Blood thinners and clot-related drugs
- Diuretics, potassium, and fluid balance
- Breathing medicines, including inhalers
- Antibiotics, antivirals, and antifungals
- Pain medicines, including opioids and NSAIDs
- Insulin, diabetes medicines, and thyroid drugs
- Medicines for mood, anxiety, sleep, and seizures
- Stomach, bowel, and bladder medicines
- Safe drug use in children, pregnancy, and older adults
- Patient teaching and monitoring
You will find multiple-choice, select-all-that-apply, and dosage questions, which are the formats pharmacology courses use most.
Why Practice Questions Help in This Course
Reading about drug classes helps you recognize names. Answering questions helps you use them. Practice helps you:
- Link each drug to its main action, its biggest risk, and the nursing action that goes with it
- Know what to check before a dose, such as a pulse, blood pressure, or lab value
- Notice early signs of toxicity before they become emergencies
- Pick the safest action when several choices sound reasonable
- Get used to how exam questions are written
Most students are not stopped by one hard idea. They are stopped by volume. Short, regular practice by chapter helps you keep more of it than a single long cram session.
What Makes This Test Bank Different
Every question includes a full rationale. You will see why the best answer is safest and why each other option is wrong, incomplete, or not the priority. On pharmacology exams the wrong answers usually sound sensible, so understanding why they fail is a big part of learning.
Questions are grouped by chapter and drug class. Review one class before a quiz, or work across several chapters before a final. It fits beside your reading, before a clinical day, or as a last review before an exam.
Sample Questions
Question 1
Before giving a scheduled dose of metoprolol, a nurse finds a heart rate of 48 beats per minute and a blood pressure of 94/58 mm Hg. The patient feels dizzy. What should the nurse do?
A. Give the dose and recheck in one hour
B. Hold the dose and notify the provider
C. Give half the dose
D. Give the dose with a glass of water to raise the blood pressure
Correct Answer: B
Rationale: Metoprolol is a beta-blocker that slows the heart and lowers blood pressure. A heart rate under 60, low blood pressure, and dizziness mean the drug could be causing too much effect. Giving it could make the patient worse. The nurse should hold the dose and report the findings. Giving half the dose is not within the nurse’s authority and still carries risk. Water will not correct the effect of the drug.
Question 2
A patient taking warfarin has an INR of 5.2 and has no bleeding. Which finding does the nurse recognize as the most important to report?
A. A mild headache
B. New black, tarry stools
C. A dry mouth
D. A small bruise on the arm
Correct Answer: B
Rationale: An INR of 5.2 is above the usual range of 2 to 3, so the patient is at higher risk of bleeding. Black, tarry stools suggest bleeding in the stomach or upper bowel and need to be reported right away. The provider may hold the drug or give vitamin K. A mild headache, dry mouth, and a small bruise are less urgent, though the headache should still be watched since a sudden severe headache could mean bleeding in the brain.
Question 3
A patient is prescribed oral furosemide and has a potassium level of 3.1 mEq/L. Which sign should the nurse watch for?
A. Muscle weakness and an irregular heartbeat
B. Tall, peaked T waves on the monitor
C. Excess thirst only
D. Dry skin and hair
Correct Answer: A
Rationale: Furosemide causes the body to lose potassium. A level of 3.1 is low, and hypokalemia can cause muscle weakness, cramps, constipation, and dangerous heart rhythms. The nurse should report the level and expect orders for potassium replacement. Tall, peaked T waves are a sign of high potassium. Thirst and dry skin are not typical signs of low potassium.
Question 4
A nurse is teaching a patient who has just been prescribed amoxicillin for a throat infection. Which statement shows that the patient needs more teaching?
A. “I will take all of the pills, even if I feel better in two days.”
B. “I will call if I develop a rash, hives, or trouble breathing.”
C. “I can save leftover pills to use the next time I am sick.”
D. “I will space the doses evenly through the day.”
Correct Answer: C
Rationale: Leftover antibiotics should not be saved for later. Taking them without a diagnosis can delay proper treatment, cause side effects, and add to antibiotic resistance. Finishing the full course, reporting allergic signs, and spacing doses evenly are all correct. The nurse should correct the misunderstanding and explain how to dispose of unused medicine safely.
Question 5
A nurse is giving regular insulin and NPH insulin in one syringe. Which step is correct?
A. Draw up the NPH first, then the regular insulin
B. Draw up the regular insulin first, then the NPH
C. Inject air only into the regular insulin vial
D. Shake both vials hard before drawing up
Correct Answer: B
Rationale: The clear insulin (regular) is drawn up first, then the cloudy insulin (NPH), which is often remembered as “clear before cloudy.” This prevents NPH from getting into the regular insulin vial and changing how fast it works. Air is injected into both vials before drawing up. NPH should be gently rolled, not shaken hard, because shaking can create bubbles and make dosing inaccurate.
Frequently Asked Questions
Is this the same as the publisher’s official test bank?
No. This is an independently written study resource meant to help you review the topics in the 20th edition of Clayton’s Basic Pharmacology for Nurses. It is a self-study companion and is not distributed by the publisher.
Will it help me prepare for the NCLEX-RN?
Yes. The scenario style is similar to licensure exam questions. It focuses on safe administration, priority actions, and patient teaching.
Does it cover every chapter?
Yes. The questions follow the chapter order of the 20th edition, from basic pharmacology and safe administration through each major drug class and special groups.
What kinds of questions are included?
Mostly multiple-choice, plus select-all-that-apply and dosage questions.
Are there explanations?
Yes. Every question has a full rationale that explains why the best answer is correct and why the other options are not.
Who is it for?
Nursing students taking a pharmacology course, and anyone reviewing drug safety before an exam or the NCLEX.
How should I use it?
Read the chapter first, then try the questions before looking at the answers. Study the rationales for anything you missed, since knowing why an answer is correct helps more than memorizing the letter.
Can it replace the textbook?
No. It works best alongside the textbook. The book teaches the drug classes, and the test bank gives you practice applying them.
Is it matched to the 20th edition?
Yes. It follows the topics and chapter structure of the 20th edition.
Is it useful the night before an exam?
Yes. Because it is organized by chapter and drug class, you can quickly review one area, such as insulin or blood thinners, without rereading the whole book.







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